BDBM566626 3-fluoro-5-((1,3,3-trifluoro-2a-hydroxy-2,2a,3,4- tetrahydro-1H-cyclopenta[cd]inden-5- yl)oxy)benzonitrile::US11420936, Compound 19

SMILES OC12CC(F)c3ccc(Oc4cc(F)cc(c4)C#N)c(CC1(F)F)c23

InChI Key InChIKey=CVWSOBBRTRUOPE-UHFFFAOYSA-N

Data  1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 566626   

TargetVascular endothelial growth factor A(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM566626(3-fluoro-5-((1,3,3-trifluoro-2a-hydroxy-2,2a,3,4- ...)
Affinity DataEC50:  4.10E+3nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
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Date in BDB:
11/6/2022
Entry Details
Go to US Patent