BDBM566625 3-fluoro-5-((1,1,2a,3,3,4,4-heptafluoro-2,2a,3,4- tetrahydro-1H-cyclopenta[cd]inden-7- yl)oxy)benzonitrile::US11420936, Compound 15

SMILES Fc1cc(Oc2ccc3c4c2C(F)(F)CC4(F)C(F)(F)C3(F)F)cc(c1)C#N

InChI Key InChIKey=BNNQWTDEIRQIEE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 566625   

TargetVascular endothelial growth factor A(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM566625(3-fluoro-5-((1,1,2a,3,3,4,4-heptafluoro-2,2a,3,4- ...)
Affinity DataEC50: >5.00E+3nMAssay Description:The ability of the disclosed compounds to inhibit HIF-2α was measured by determining VEGF expression in 786-O cells. About 7500 786-O cells were...More data for this Ligand-Target Pair
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Date in BDB:
11/6/2022
Entry Details
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