BDBM566470 US11419874, Example 20

SMILES Cc1cnc2c(cnn2c1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)cc1)C(C)(C)O

InChI Key InChIKey=NPARLOLYJZFLKX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 566470   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566470(US11419874, Example 20)
Affinity DataIC50: 5.10nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Oslo University Hospital

US Patent
LigandPNGBDBM566470(US11419874, Example 20)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of PDE2A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed