BDBM565701 N-(methylsulfonyl)-5-(4- (trifluoromethyl)phenoxy)-2- naphthamide::US11420935, Compound 5

SMILES CS(=O)(=O)NC(=O)c1ccc2c(Oc3ccc(cc3)C(F)(F)F)cccc2c1

InChI Key InChIKey=HOWGIASRFJITIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 565701   

TargetLuciferin 4-monooxygenase(Southern Russian firefly)
Vivace Therapeutics

US Patent
LigandPNGBDBM565701(N-(methylsulfonyl)-5-(4- (trifluoromethyl)phenoxy)...)
Affinity DataIC50: 100nMAssay Description:The Dual-Glo Luciferase Reagent was prepared by transferring the contents of one bottle of Dual-Glo Luciferase Buffer to one bottle of Dual-Glo Lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent

TargetTranscriptional coactivator YAP1(Homo sapiens)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM565701(N-(methylsulfonyl)-5-(4- (trifluoromethyl)phenoxy)...)
Affinity DataIC50: 100nMAssay Description:Inhibition of YAP in HEK293T cells incubated for 24 hrs by Promega Dual-Luciferase Reporter AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed