BDBM565204 2-(3-(4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile::US11414413, Example 1

SMILES CCS(=O)(=O)N1CC(CC#N)(C1)n1cc(cn1)-c1c[nH]c2ncccc12

InChI Key InChIKey=SMDHVPIOXSAYEX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 565204   

TargetTyrosine-protein kinase JAK1(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM565204(US11414413, Example 1 | 2-(3-(4-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 20nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM565204(US11414413, Example 1 | 2-(3-(4-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 35nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Suzhou Longbiotech Pharmaceuticals

US Patent
LigandPNGBDBM565204(US11414413, Example 1 | 2-(3-(4-(1H-pyrrolo[2,3-b]...)
Affinity DataIC50: 50nMAssay Description:The study of the effect of compounds on the activity of purified recombinant JAK was performed by studying the inhibitory activity of the compounds o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent