BDBM564683 US11414384, Example 169 Isomer 2::US11414384, Example 170 Isomer 2

SMILES CC(NC(=O)c1ccc2c(c[nH]c2c1)C(=O)[C@H](NCCc1ccc(cc1)C#N)c1ccccc1)C(F)(F)F

InChI Key InChIKey=XGBNNEZVBIKAQY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 564683   

LigandPNGBDBM564683(US11414384, Example 169 Isomer 2 | US11414384, Exa...)
Affinity DataIC50: 87.1nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

LigandPNGBDBM564683(US11414384, Example 169 Isomer 2 | US11414384, Exa...)
Affinity DataIC50: 4.11E+3nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent