BDBM564436 US11414384, Example 126 Isomer 2

SMILES CN1CCC(CC1)Oc1ccc2c(c[nH]c2c1)C(=O)[C@H](NCCc1ccc(cc1)C#N)c1ccccc1

InChI Key InChIKey=HEVOBGUQPMCOCP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 564436   

TargetHistone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit(Human)
Constellation Pharmaceuticals

US Patent

LigandBDBM564436(US11414384, Example 126 Isomer 2)Copy SMILESCopy InChI

Affinity DataIC50: 36.2nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/30/2022
Entry Details
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