BDBM564418 US11414384, Example 121 Isomer 2::US11414384, Example 122 Isomer 2

SMILES CN1CCN(CC1)c1ccc2c(c[nH]c2c1)C(=O)[C@H](NCCc1ccc(cc1)C#N)c1ccccc1

InChI Key InChIKey=BRDWGDCKTCQZHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 564418   

LigandPNGBDBM564418(US11414384, Example 121 Isomer 2 | US11414384, Exa...)
Affinity DataIC50: 82nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent

LigandPNGBDBM564418(US11414384, Example 121 Isomer 2 | US11414384, Exa...)
Affinity DataIC50: 44nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
Go to US Patent