BDBM563664 1-[5-(2-Hydroxy-1,1-dimethyl- ethyl)-2-p-tolyl-2H-pyrazol-3-yl]- 3-[4-(pyridin-4-yloxy)-phenyl]- urea::US11407771, Compound 280

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccncc2)cc1)C(C)(C)CO

InChI Key InChIKey=WQGFCOHRFHVPPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563664   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563664(US11407771, Compound 280 | 1-[5-(2-Hydroxy-1,1-dim...)
Affinity DataIC50: 625nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563664(US11407771, Compound 280 | 1-[5-(2-Hydroxy-1,1-dim...)
Affinity DataIC50: 94nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent