BDBM563647 N-(4-{4-[3-(5-tert-Butyl-2- methyl-2H-pyrazol-3-yl)-ureido]- 3-fluoro-phenoxy}-pyridin-2-yl)- acetamide::US11407771, Compound 391

SMILES CC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(nn3C)C(C)(C)C)c(F)c2)ccn1

InChI Key InChIKey=FOKDTUHZKJGPII-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 563647   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563647(US11407771, Compound 391 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563647(US11407771, Compound 391 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 6nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563647(US11407771, Compound 391 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 6nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563647(US11407771, Compound 391 | N-(4-{4-[3-(5-tert-Buty...)
Affinity DataIC50: 6nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent