BDBM563635 N-[4-[3-fluoro-4-[[5-(3- methyloxetan-3-yl)-2-(p- tolyl)pyrazol-3- yl]carbamoylamino]phenoxy]-2- pyridyl]-2-methoxy-acetamide::US11407771, Compound 267

SMILES COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(cn3-c3ccc(C)cc3)C3(C)COC3)c(F)c2)ccn1

InChI Key InChIKey=FEEMWRIUZZAZSB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563635   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563635(US11407771, Compound 267 | N-[4-[3-fluoro-4-[[5-(3...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
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TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563635(US11407771, Compound 267 | N-[4-[3-fluoro-4-[[5-(3...)
Affinity DataIC50: 19nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent