BDBM563633 1-[5-tert-Butyl-2-(4-fluoro- phenyl)-2H-pyrazol-3-yl]-3-[2- fluoro-4-(pyridin-4-yloxy)- phenyl]-urea::US11407771, Compound 303

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccncc3)cc2F)n(n1)-c1ccc(F)cc1

InChI Key InChIKey=CHWCBYFSAVGKEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563633   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563633(US11407771, Compound 303 | 1-[5-tert-Butyl-2-(4-fl...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563633(US11407771, Compound 303 | 1-[5-tert-Butyl-2-(4-fl...)
Affinity DataIC50: 23nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent