BDBM563627 N-[4-(3-fluoro-4-{3-[5-(3- methyl-thietan-3-yl)-2-p-tolyl- 2H-pyrazol-3-yl]-ureido}- phenoxy)-pyridin-2-yl]-2- methoxy-acetamide::US11407771, Compound 268

SMILES COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(cn3-c3ccc(C)cc3)C3(C)CSC3)c(F)c2)ccn1

InChI Key InChIKey=MALUSUBCURFUCG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563627   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563627(US11407771, Compound 268 | N-[4-(3-fluoro-4-{3-[5-...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563627(US11407771, Compound 268 | N-[4-(3-fluoro-4-{3-[5-...)
Affinity DataIC50: 40nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent