BDBM563624 N-[4-[2-[2-[[5-tert-butyl-2-(3- fluoropholyl)pyrazol-3- yl]carbamoylamino]thiazol-5- yl]ethyl]-2-pyridyl]-2-hydroxy- acetamide::US11407771, Compound 321

SMILES CC(C)(C)c1cc(NC(=O)Nc2ncc(CCc3ccnc(NC(=O)CO)c3)s2)n(n1)-c1cccc(F)c1

InChI Key InChIKey=GUTITRZSWQFLSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563624   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563624(US11407771, Compound 321 | N-[4-[2-[2-[[5-tert-but...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563624(US11407771, Compound 321 | N-[4-[2-[2-[[5-tert-but...)
Affinity DataIC50: 67nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent