BDBM563623 1-(5-tert-Butyl-2-p-tolyl-2H- pyrazol-3-yl)-3-[2-fluoro-4-(3- methyl-pyridin-4-yloxy)-phenyl]- urea::US11407771, Compound 300

SMILES Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccncc2C)cc1F)C(C)(C)C

InChI Key InChIKey=XXHHVHVEBOJTAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563623   

TargetMitogen-activated protein kinase 13(Human)
Washington University

US Patent
LigandPNGBDBM563623(US11407771, Compound 300 | 1-(5-tert-Butyl-2-p-tol...)
Affinity DataIC50: 250nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Washington University

US Patent
LigandPNGBDBM563623(US11407771, Compound 300 | 1-(5-tert-Butyl-2-p-tol...)
Affinity DataIC50: 67nMAssay Description:ach of these analogs were checked for physical chemical characteristics based on molecular weight, Lipinski's Rule of 5, partition coefficient (l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent