BDBM563536 (S)-2-amino-3-(4-(2- amino-4-((R)-1-(4- chloro-2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)thieno [3,2-d]pyrimidine-7- yl)phenyl)propionic acid hydrochloride::US11407763, Example 91

SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1nc(N)nc2c(csc12)-c1ccc(C[C@H](N)C(O)=O)cc1)C(F)(F)F

InChI Key InChIKey=BIXIMYYKYTWADM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563536   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563536((S)-2-amino-3-(4-(2- amino-4-((R)-1-(4- chloro-2-(...)
Affinity DataIC50: 208nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
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Date in BDB:
11/5/2022
Entry Details
Go to US Patent