BDBM563526 8-(4-((R)-1-(4-chloro- 2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)thieno [3,2-d]pyrimidine-7-yl)- 2-azaspiro[4.5]dec-7- ene-3-carboxylic acid hydrochloride::US11407763, Example 84

SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1ncnc2c(csc12)C1=CCC2(CNC(C2)C(O)=O)CC1)C(F)(F)F

InChI Key InChIKey=PBZQONAPQNZDEX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563526   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563526(8-(4-((R)-1-(4-chloro- 2-(3-methyl-1H- pyrazole-1-...)
Affinity DataIC50: 307nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
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Date in BDB:
11/5/2022
Entry Details
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