BDBM563515 8-(2-amino-6-((R)-1-(4- chloro-2-(3,6-dihydro- 2H-pyran-4-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)-2- azaspiro[4.5]dec-7-ene- 3-carboxylic acid hydrochloride::US11407763, Example 83

SMILES Nc1nc(O[C@H](c2ccc(Cl)cc2C2=CCOCC2)C(F)(F)F)cc(n1)C1=CCC2(CNC(C2)C(O)=O)CC1

InChI Key InChIKey=ZIEDFKQMFAUDHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563515   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563515(8-(2-amino-6-((R)-1-(4- chloro-2-(3,6-dihydro- 2H-...)
Affinity DataIC50: 1.15E+3nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
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Date in BDB:
11/5/2022
Entry Details
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