BDBM563511 (2S)-2-amino-3-(4-(2- amino-6-((R)-1-(5- chloro-4',4'difluoro- 2',3',4',5'-tetrahydro- [1,1'-biphenyl]-2-yl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)cyclohex-3- ene-1-yl)propionic acid hydrochloride::US11407763, Example 75

SMILES N[C@@H](CC1CCC(=CC1)c1cc(O[C@H](c2ccc(Cl)cc2C2=CCC(F)(F)CC2)C(F)(F)F)nc(N)n1)C(O)=O

InChI Key InChIKey=DPZSVAPRJNCZEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563511   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563511((2S)-2-amino-3-(4-(2- amino-6-((R)-1-(5- chloro-4'...)
Affinity DataIC50: 443nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
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Date in BDB:
11/5/2022
Entry Details
Go to US Patent