BDBM563509 (S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2- (5,6-dihydro-2H-pyran- 3-yl)phenyl)-2,2,2- trifluoroethoxy)thieno [3,2-d]pyrimidine-7- yl)phenyl)propionic acid hydrochloride::US11407763, Example 69::US11407763, Example 70

SMILES N[C@@H](Cc1ccc(cc1)-c1csc2c(O[C@H](c3ccc(Cl)cc3C3=CCCOC3)C(F)(F)F)ncnc12)C(O)=O

InChI Key InChIKey=VVEXHDYBQYYFMG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563509   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563509((S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2- (5,6-dihy...)
Affinity DataIC50: 263nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563509((S)-2-amino-3-(4-(4- ((R)-1-(4-chloro-2- (5,6-dihy...)
Affinity DataIC50: 371nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent