BDBM563506 (2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-(5,6-dihydro- 2H-pyran-3-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)cyclohex-3- ene-1-yl)propionic acid hydrochloride::US11407763, Example 66::US11407763, Example 67

SMILES N[C@@H](CC1CCC(=CC1)c1cc(O[C@H](c2ccc(Cl)cc2C2=CCCOC2)C(F)(F)F)nc(N)n1)C(O)=O

InChI Key InChIKey=KAJJWJORNRYNTM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563506   

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563506(US11407763, Example 67 | (2S)-2-amino-3-(4-(2- ami...)
Affinity DataIC50: 125nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent

TargetTryptophan 5-hydroxylase 1(Human)
Gwangju Institute of Science and Technology

US Patent
LigandPNGBDBM563506(US11407763, Example 67 | (2S)-2-amino-3-(4-(2- ami...)
Affinity DataIC50: 91nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2022
Entry Details
Go to US Patent