BDBM563503 (2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-(5,6-dihydro- 2H-pyran-3-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)cyclohex-3-ene- 1-yl)propionic acid::US11407768, Compound 30

SMILES OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNC(=O)c1ccc(cc1)-c1ccc(cc1)-c1cc2nc(O[C@@H]3CO[C@@H]4[C@H](O)CO[C@H]34)[nH]c2cc1Cl

InChI Key InChIKey=VGGLMRQQHQXFHB-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 563503   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Kallyope

US Patent

LigandBDBM563503(US11407768, Compound 30 | (2S)-2-amino-3-(4-(2- am...)Copy SMILESCopy InChI

Affinity DataEC50:  0.650nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/5/2022
Entry Details
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