BDBM563495 (2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)cyclohex-3- ene-1-yl)propionic acid hydrochloride::(2S)-2-amino-3-(4-(2- amino-6-((R)-1-(4- chloro-2-(3-methyl-1H- pyrazole-1-yl)phenyl)- 2,2,2- trifluoroethoxy)pyrimidine- 4-yl)cyclohex-3- ene-1-yl)propionic acid::US11407763, Example 31::US11407763, Example 45::US11407768, Compound 11
SMILES Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)C1=CCC(C[C@H](N)C(O)=O)CC1)C(F)(F)F
InChI Key InChIKey=JUMFUJZCESUTFP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 563495
Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Kallyope
US Patent
Kallyope
US Patent
Affinity DataEC50: 0.460nMAssay Description:Compound effect on AMPK enzyme activation was determined in a cell-free format with a 12-point concentration curve. The ADP-Glo detection system was ...More data for this Ligand-Target Pair
Affinity DataIC50: 114nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:In order to confirm the inhibitory effect of the compound represented by formula 1 according to the present invention on the tryptophan hydroxylase a...More data for this Ligand-Target Pair