BDBM563487 US11407760, Example 36

SMILES Fc1ccc(NC(=O)C2(CC2)C(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CCOCC5)c5OCCOc5c34)cc2Cl)cc1

InChI Key InChIKey=XZOAILUFNUBENW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 563487   

TargetHepatocyte growth factor receptor(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM563487(US11407760, Example 36)
Affinity DataIC50: 50nMAssay Description:The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds: a total of 11 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Beijing Scitech-Mq Pharmaceuticals

US Patent
LigandPNGBDBM563487(US11407760, Example 36)
Affinity DataIC50: 275nMAssay Description:The assay is based on the LANCE TR-FRET technology of Perkin Elmer Inc., and the assay method is as follows:1. Dilution of compounds: a total of 11 c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent