BDBM563326 3-(2,6-difluoro-3-hydroxy-5-methoxyphenyl)-1-ethyl-8-(morpholinomethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[4,3-d]pyrimidin-2-one ::US11407750, Compound 2

SMILES CCN1C(=O)N(Cc2cnc3[nH]c(CN4CCOCC4)cc3c12)c1c(F)c(O)cc(OC)c1F

InChI Key InChIKey=IQFLJVNHOXGXGX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 563326   

TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent
LigandPNGBDBM563326(US11407750, Compound 2 | 3-(2,6-difluoro-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 2(Human)
Incyte

US Patent
LigandPNGBDBM563326(US11407750, Compound 2 | 3-(2,6-difluoro-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent
LigandPNGBDBM563326(US11407750, Compound 2 | 3-(2,6-difluoro-3-hydroxy...)
Affinity DataIC50: 10nMAssay Description:The inhibitor potency of the exemplified compounds was determined in an enzyme discontinuous assay that measures peptide phosphorylation using FRET m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent