BDBM562998 US11407736, Compound I-194

SMILES C[C@H](N)C(=O)OC1(COC1)C#Cc1ccc2OC[C@H](NC(=O)c3cc(Oc4ccccc4)ccn3)C(=O)N(C)c2c1

InChI Key InChIKey=BWGQXWHWQUUSKV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562998   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM562998(US11407736, Compound I-194)
Affinity DataIC50: 18.6nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
Go to US Patent