BDBM562992 US11407736, Compound I-191

SMILES CN1c2cc(ccc2OC[C@H](NC(=O)c2cc(Oc3ccccc3)ccn2)C1=O)C#CC1(F)CN(C1)C(C)=O

InChI Key InChIKey=BEMQIEWGJOIXOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562992   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM562992(US11407736, Compound I-191)
Affinity DataIC50: 19.7nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent