BDBM562951 US11407736, Compound I-128

SMILES COC1(COC1)C#Cc1ccc2OC[C@H](NC(=O)c3cc(Oc4ccccc4)ccn3)C(=O)N(C)c2c1

InChI Key InChIKey=VARQWALGRZPWTN-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562951   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent

LigandBDBM562951(US11407736, Compound I-128)Copy SMILESCopy InChI

Affinity DataIC50: 19.7nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2022
Entry Details
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