BDBM562935 US11407736, Compound I-112

SMILES CN1c2cc(ccc2OCC(NC(=O)c2cc(Oc3ccccc3F)ccn2)C1=O)C#CC1(O)COC1

InChI Key InChIKey=OWDAZPMRRMWTIL-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562935   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent

LigandBDBM562935(US11407736, Compound I-112)Copy SMILESCopy InChI

Affinity DataIC50: 15.1nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/28/2022
Entry Details
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