BDBM562831 2-((2S,5R,6S)-6-(3-Chlorophenyl)-5-(4-chlorophenyl)-4-((S)-1-hydroxybutan-2-yl)-3-oxomorpholin-2-yl)acetic acid or 2-((2R,5R,6S)-6-(3-chlorophenyl)-5-(4-chlorophenyl)-4-((S)-1-hydroxybutan-2-yl)-3-oxomorpholin-2-yl)acetic acid::US11407721, Example 78

SMILES CC[C@@H](CO)N1[C@@H]([C@@H](O[C@H](CC(O)=O)C1=O)c1cccc(Cl)c1)c1ccc(Cl)cc1

InChI Key InChIKey=GOJFTLJDUNFYCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562831   

TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Human)
Amgen

US Patent
LigandPNGBDBM562831(US11407721, Example 78 | 2-((2S,5R,6S)-6-(3-Chloro...)
Affinity DataIC50: 611nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
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Date in BDB:
10/28/2022
Entry Details
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