BDBM562553 US11407736, Compound I-1::US11472782, Compound I-1

SMILES CCOC(=O)CCc1ccc2OCC(NC(=O)c3n[nH]c(Cc4ccccc4)n3)C(=O)N(C)c2c1

InChI Key InChIKey=KNKXMTRZCZERDE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562553   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM562553(US11407736, Compound I-1 | US11472782, Compound I-...)
Affinity DataIC50: 19nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2022
Entry Details
Go to US Patent

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM562553(US11407736, Compound I-1 | US11472782, Compound I-...)
Affinity DataIC50: 19nMAssay Description:ADP-Glo (Promega, Madison, Wis., USA) reagents were thawed at ambient temperature. Kinase Detection Reagent was prepared by mixing kinase detection b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2022
Entry Details
Go to US Patent