BDBM562344 (rac)-12-Ethyl-11-methyl-1-(3-(naphthalen-1-yloxy)propyl)-4,5,6,8,9,11-hexahydropyrazolo[3′,4′:4,5][1,2,8]thiadiazacycloundecino[6,7,8-hi]indole-2-carboxylic acid 7,7-dioxide::US11401278, Example 17

SMILES CCc1c-2c(CNS(=O)(=O)CCCn3c(C(O)=O)c(CCCOc4cccc5ccccc45)c4cccc-2c34)nn1C

InChI Key InChIKey=WSCLIUZENSUOMD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 562344   

LigandPNGBDBM562344(US11401278, Example 17 | (rac)-12-Ethyl-11-methyl-...)
Affinity DataIC50: 8.10nMAssay Description:MCL-1/Noxa BH3 Peptide (MCL-1 Assay): From there, 50 nl were transferred in a dark test plate (Greiner Bio-One, Frickenhausen, Germany). The assay wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent

LigandPNGBDBM562344(US11401278, Example 17 | (rac)-12-Ethyl-11-methyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:BCL-2/Bad BH3 Peptide (BCL-2 Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-2 solution (usually for a 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent

LigandPNGBDBM562344(US11401278, Example 17 | (rac)-12-Ethyl-11-methyl-...)
Affinity DataIC50: 2.00E+4nMAssay Description:BCL-XL/Bad BH3 Peptide (BCL-XL Assay): The assay was initiated by addition of 2 μl of a 2.5-fold concentrated His-BCL-XL solution (usually for a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2022
Entry Details
Go to US Patent