BDBM562299 (S)-2-methyl-5-(2- methyl-4-(3- (methylamino)-1- (thiophen-2- yl)propoxy)benzyl)- 5,6,7,8-tetrahydro-4H- pyrazolo[1,5- a][1,4]diazepin-4-one::US11401270, Example 124

SMILES CNCC[C@H](Oc1ccc(CN2CCCn3nc(C)cc3C2=O)c(C)c1)c1cccs1

InChI Key InChIKey=ZLMFXBJCLZXYBB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562299   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562299(US11401270, Example 124 | (S)-2-methyl-5-(2- methy...)
Affinity DataKi: <100nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2022
Entry Details
Go to US Patent