BDBM562281 (S)-1-methyl-4-(2- methyl-4-(3- (methylamino)-1- (thiophen-2- yl)propoxy)benzyl)- 1,2,3,4-tetrahydro-5H- pyrido[2,3- e][1,4]diazepin-5-one::US11401270, Example 107

SMILES CNCC[C@H](Oc1ccc(CN2CCN(C)c3ncccc3C2=O)c(C)c1)c1cccs1

InChI Key InChIKey=HAIYGSFSDQPGAA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 562281   

TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM562281(US11401270, Example 107 | (S)-1-methyl-4-(2- methy...)
Affinity DataKi: <100nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair
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Date in BDB:
10/23/2022
Entry Details
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