BDBM562034 (S)-2-(1-Cyclopropyl- ethyl)-5-(6-(3-methyl- 1H-pyrazol-5-yl)pyri- dazin-4-yl)-7-(methyl- sulfonyl)isoindolin-1- one, trifluoroacetate salt::US11396502, Example 10

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1cnnc(c1)-c1cc(C)n[nH]1

InChI Key InChIKey=FDQWDYKZBRNJOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562034   

LigandPNGBDBM562034(US11396502, Example 10 | (S)-2-(1-Cyclopropyl- eth...)
Affinity DataIC50: 500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent

LigandPNGBDBM562034(US11396502, Example 10 | (S)-2-(1-Cyclopropyl- eth...)
Affinity DataIC50: 2.00E+3nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent