BDBM562015 (S)-2-(1-Cyclopropylethyl)-5-(2- (5-(3-hydroxyazetidine-1- carbonyl)-4-methyl-1H-imidazol- 2-yl)pyridin-4-yl)-7- (methylsulfonyl)isoindolin-1-one, trifluoroacetate salt::US11396502, Example 7e

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1ccnc(c1)-c1nc(C)c([nH]1)C(=O)N1CC(O)C1

InChI Key InChIKey=CRUUIPUMKUWHPC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562015   

LigandPNGBDBM562015(US11396502, Example 7e | (S)-2-(1-Cyclopropylethyl...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent

LigandPNGBDBM562015(US11396502, Example 7e | (S)-2-(1-Cyclopropylethyl...)
Affinity DataIC50: 500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent