BDBM562013 (S)-N-(Bicyclo[1.1.1]pentan-1- yl)-2-(4-(2-(1-cyclopropylethyl)- 7-(methylsulfonyl)-1- oxoisoindolin-5-yl)pyridin-2-yl)- 4-methyl-1H-imidazole-5-::US11396502, Example 7c

SMILES C[C@@H](C1CC1)N1Cc2cc(cc(c2C1=O)S(C)(=O)=O)-c1ccnc(c1)-c1nc(C)c([nH]1)C(=O)NC12CC(C1)C2

InChI Key InChIKey=NASGJBSOQMADGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 562013   

LigandPNGBDBM562013(US11396502, Example 7c | (S)-N-(Bicyclo[1.1.1]pent...)
Affinity DataIC50: 100nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent

LigandPNGBDBM562013(US11396502, Example 7c | (S)-N-(Bicyclo[1.1.1]pent...)
Affinity DataIC50: 500nMAssay Description:The kinase reaction was conducted in polystyrene 384-well Greiner Bio-one white plate from Thermo Fisher Scientific in a final volume of 25 μL. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent