BDBM561994 BDBM50538480::US11396496, Compound C2

SMILES COc1ccc(cc1)S(=O)(=O)Cc1ccc(N(CC(O)=O)S(=O)(=O)c2ccc(OC)cc2)c2ccccc12

InChI Key InChIKey=ZPWOSQULANINNR-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561994   

TargetKelch-like ECH-associated protein 1(Human)
University of Illinois At Chicago

Curated by ChEMBL

LigandBDBM561994(US11396496, Compound C2 | BDBM50538480)Copy SMILESCopy InChI

Affinity DataIC50: 678nMAssay Description:Inhibition of FITC-9mer Nrf2 peptide binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) b...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
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TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
University of Illinois

US Patent

LigandBDBM561994(US11396496, Compound C2 | BDBM50538480)Copy SMILESCopy InChI

Affinity DataIC50: 698nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/17/2022
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL