BDBM561989 BDBM50537616::US11396496, Compound A7

SMILES COc1ccc(cc1)S(=O)(=O)Nc1cnc(N(C(C)C(O)=O)S(=O)(=O)c2ccc(OC)cc2)c2ccccc12

InChI Key InChIKey=WTDFQAGJWVTDFA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561989   

TargetNuclear factor erythroid 2-related factor 2(Human)
TBA

Curated by ChEMBL

LigandBDBM561989(US11396496, Compound A7 | BDBM50537616)Copy SMILESCopy InChI

Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Keap1-Nrf2 Interaction (unknown origin) by fluorescence anisotropyMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetKelch-like ECH-associated protein 1/Nuclear factor erythroid 2-related factor 2(Human)
University of Illinois

US Patent

LigandBDBM561989(US11396496, Compound A7 | BDBM50537616)Copy SMILESCopy InChI

Affinity DataIC50: 2.30E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/17/2022
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL