BDBM56192 7-chloranyl-4-piperazin-1-yl-quinoline::7-chloro-4-(1-piperazinyl)quinoline::7-chloro-4-piperazin-1-ylquinoline::7-chloro-4-piperazino-quinoline::MLS000049580::SMR000076122::cid_738389

SMILES Clc1ccc2c(ccnc2c1)N1CCNCC1

InChI Key InChIKey=DNXNPMDUDGUXOB-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 56192   

TargetKallikrein-5(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM56192(7-chloro-4-piperazin-1-ylquinoline | 7-chloranyl-4...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetFermitin family homolog 1(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM56192(7-chloro-4-piperazin-1-ylquinoline | 7-chloranyl-4...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of His6-tagged KIND1 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetFermitin family homolog 2(Homo sapiens)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM56192(7-chloro-4-piperazin-1-ylquinoline | 7-chloranyl-4...)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of His6-tagged KIND2 (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence polarization methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetNeutrophil cytosol factor 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM56192(7-chloro-4-piperazin-1-ylquinoline | 7-chloranyl-4...)
Affinity DataKi:  5.83E+5nMAssay Description:Covalent inhibition of recombinant human His-tagged p47phox SH3A-B domain (151 to 285 residues) expressed in Escherichia coli BL21 (DE3) cells intera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed