BDBM56150 (6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6E)-4-methyl-6-[5-(2-methylphenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-4-methyl-6-[5-(o-tolyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phenol::MLS000099089::SMR000070479::cid_5405417

SMILES Cc1ccc(O)c(c1)-c1cc([nH]n1)-c1ccccc1C

InChI Key InChIKey=ZLYRBPNNXMKKGJ-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 56150   

TargetKallikrein-5(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetProstaglandin G/H synthase 2(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human COX-2 by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 15-LOX-2 using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human 12-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by UV-visible spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM56150(4-methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phe...)
Affinity DataKi:  1.00E+3nMAssay Description:Competitive inhibition of N-terminal His6-tagged human 12/15-LOX using arachidonic acid as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2017
Entry Details Article
PubMed