BDBM561433 3-(4-amino-2-(1-(pyridin-2-yl)ethyl)-7-(pyrimidin-4-yl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)benzonitrile::US11390624, Example 47

SMILES CC(c1ccccn1)n1nc2c(N)nc(-c3cccc(c3)C#N)c(-c3ccncn3)c2n1

InChI Key InChIKey=LJJPYMXBCNMUQS-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561433   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM561433(US11390624, Example 47 | 3-(4-amino-2-(1-(pyridin-...)
Affinity DataEC50:  550nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561433(US11390624, Example 47 | 3-(4-amino-2-(1-(pyridin-...)
Affinity DataKi: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent