BDBM561429 3-(4-amino-2-(pyridin-2-ylmethyl)-7-(quinoxalin-6-yl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)-2-fluorobenzonitrile::US11390624, Example 43

SMILES Nc1nc(-c2cccc(C#N)c2F)c(-c2ccc3nccnc3c2)c2nn(Cc3ccccn3)nc12

InChI Key InChIKey=VHJWGRRHCPJQFK-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561429   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM561429(US11390624, Example 43 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataEC50:  550nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561429(US11390624, Example 43 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataKi: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent