BDBM561417 US11390624, Example 32

SMILES Cn1cc(ccc1=O)-c1c(nc(N)c2nn(Cc3ncccc3F)nc12)-c1cccc(c1)C#N

InChI Key InChIKey=OYSQZTKBNXAYBS-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561417   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM561417(US11390624, Example 32)
Affinity DataEC50:  55nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561417(US11390624, Example 32)
Affinity DataKi: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent