BDBM561401 3-(4-amino-2-(pyridin-2-ylmethyl)-7-(pyrimidin-4-yl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)benzonitrile::US11390624, Example 16::US20250041310, Compound 13

SMILES Nc1nc(-c2cccc(c2)C#N)c(-c2ccncn2)c2nn(Cc3ccccn3)nc12

InChI Key InChIKey=UWNQHIDMVGEEFD-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 561401   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM561401(US11390624, Example 16 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
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TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561401(US11390624, Example 16 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataKi: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561401(US11390624, Example 16 | 3-(4-amino-2-(pyridin-2-y...)
Affinity DataKi: <10nMAssay Description:Assays were conducted in black low volume 384-well polystyrene plates (Greiner 784076-25) in a final volume of 10 μL. Test compounds were first seria...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent