BDBM561373 US11390610, Example 202

SMILES FC1(F)CC2(CN(C2)c2nc3ccc(cc3o2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)C1

InChI Key InChIKey=NPRWJJAJYUOLPK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561373   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM561373(US11390610, Example 202)
Affinity DataIC50: 22nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent