BDBM561366 2-[4-[3-(3-Chlorophenyl)sulfonyl-3,9-diazaspiro[5.5]undecane-9-carbonyl]piperazin-1-yl]-3H-quinazolin-4-one::US11390610, Example 195

SMILES Clc1cccc(c1)S(=O)(=O)N1CCC2(CCN(CC2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=VUFQVBRKAYTKMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561366   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM561366(US11390610, Example 195 | 2-[4-[3-(3-Chlorophenyl)...)
Affinity DataIC50: 34nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent