BDBM561090 US11390610, Example 106

SMILES COc1ccc(cc1C(F)(F)F)-c1ccc(cc1C)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=JKYFBQGZHNEFSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 561090   

TargetMonoglyceride lipase(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM561090(US11390610, Example 106)
Affinity DataIC50: 41nMAssay Description:Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
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