BDBM560565 (((((2S,3S,4R,5R)-5-(6-chloro-4-(((1R,2S)-2- methylcyclopentyl)amino)-1H-pyrazolo[3,4- d]pyrimidin-1-yl)-3,4- dihydroxytetrahydrofuran-2- yl)methyl)sulfonyl)methyl)phosphonic acid::US11377469, Example 134

SMILES C[C@H]1CCC[C@H]1Nc1nc(Cl)nc2n(ncc12)[C@@H]1O[C@H](CS(=O)(=O)CP(O)(O)=O)[C@@H](O)[C@H]1O

InChI Key InChIKey=VNXMXTMEUWAKCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560565   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM560565(US11377469, Example 134 | (((((2S,3S,4R,5R)-5-(6-c...)
Affinity DataIC50: 500nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 2 5 mM Tris-HCL, pH 7.4, 0.01...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent