BDBM560472 ((((2R,3S,4R,5R)-5-(2-chloro-4-((2- chlorobenzyl)amino)-7H-pyrrolo[2,3- d]pyrimidin-7-yl)-3,4- dihydroxytetrahydrofuran-2- yl)methoxy)methyl)phosphonic acid::US11377469, Example 40

SMILES O[C@@H]1[C@@H](COCP(O)(O)=O)O[C@H]([C@@H]1O)n1ccc2c(NCc3ccccc3Cl)nc(Cl)nc12

InChI Key InChIKey=SIEGCDJFWGGTEW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 560472   

Target5'-nucleotidase(Human)
Oric Pharmaceuticals

US Patent
LigandPNGBDBM560472(US11377469, Example 40 | ((((2R,3S,4R,5R)-5-(2-chl...)
Affinity DataIC50: 500nMAssay Description:Assay Reaction ConditionsAssay Volume: 70 μlReaction Volume: 50 μlCD73: 0.3208 nMAMP: 15 μMAssay Buffer: 2 5 mM Tris-HCL, pH 7.4, 0.01...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2022
Entry Details
US Patent